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Diabetes gene research enters `exciting stage'

Our Bureau

Hyderabad , May 1

AMID alarming rise in diabetes among the non-communicable diseases in the Indian subcontinent, Dr Mohan's M.V. Diabetes Specialities Centre claims to have recorded `exciting finding' of several genes that make Indians more susceptible to diabetes.

Announcing this here on Saturday, the Centre's Chairman, Prof V. Mohan, said the collaborative gene expression research taken up with the Indian Institute of Science, Bangalore, has entered `exciting stage' to announce `exciting data' in the next 4-8 weeks.

Declining to throw further details on the exact findings of collaborative research with IISc, Bangalore, Prof Mohan said the findings would enable the centre to come up with clear risk analysis of Indians pertaining to diabetes. With the help of the findings, the Centre would identify people with high risk, moderate risk and absolutely risk-free.

According to Prof Mohan, PPAR-Gamma gene in whites was found to protect them from diabetes. Interestingly, the Indians with PPAR-Gamma gene were deprived of such advantages. The reasons for this phenomenon were expected to be unveiled in the next stage of research, he said.

Prof Mohan, who was here to announce the opening of a full-fledged branch of Dr Mohan's M.V. Diabetes Specialities Centre at Hyderabad, said it would be a world-class centre of excellence for care in diabetes and its complications under one roof.

Elaborating the sharp increase in diabetes in India, he said nearly 52 per cent of deaths in the country are attributed to non-communicable diseases, of which diabetes was highly prominent. India has earned the dubious distinction of diabetes capital of the world.

According to the figures announced by the World Health Organisation, India had 31.7-million diabetes patients in 2000, which is expected to spurt to 79.4-million by 2030.

According to Prof Mohan, even in India, south Indians were more prone to diabetes, the exact reasons of which were still being researched. On the prevalence of diabetes, he said Hyderabad tops the list with 16 per cent, followed by Chennai with 13.9 per cent, Kolkata 12.4 per cent, Mumbai 12.2 per cent, Bangalore 11.9 per cent and Delhi with 10.5 per cent.

Expressing serious apprehensions on the economic burden of diabetes on India, Prof Mohan said it was estimated at around Rs 15,900 crore in 2000 and expected to reach Rs 79,400 crore by 2030. Coupled with other complications followed by diabetes, the economic burden was estimated to reach Rs 1,68,725 crore by 2030, he said.

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