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Nicholas Piramal's cancer drug enters phase-I/II trials

Our Bureau

Mumbai , July 15

DRUG major Nicholas Piramal India Ltd has said that its prospective anti-cancer drug molecule has entered into Phase I and II clinical studies.

"After obtaining the necessary permissions from the Canadian regulatory authorities, a patient was recently infused intravenously with P276-00 at an Oncology centre in Canada," a note from the company said.

Further, it added that it could take 9-12 months to enrol 30-35 patients to complete the Phase I/II study that will help determine a safe and possible efficacious dose, which will be used for further clinical studies.

The prospective cancer drug molecule is the first in a series of compounds from the company's research centre to enter into clinical trials. It is an inhibitor of a key protein that is required by the cells to divide.

Based on the initial laboratory data, P276-00 appears suitable as an agent to treat lung, breast and colon cancers, the note said.

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