The Hindu Business Line : Livestock Board, Sree Chitra Institute launch joint venture

The Kerala Livestock Development Board (KLDB) and Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) have launched a joint venture project for developing de-cellularised animal tissues for cardiovascular applications.

The project envisages producing de-cellularised animal tissues from bovine pericardium and bovine jugular vein for paediatric cardiac surgery. The quality animal tissues for use in the project will be sourced from male animals reared in Kerala at KLDB’s farms and slaughtered for meat purpose.

According to Mr Ani S. Das, Managing Director of KLDB, animal tissues of biomedical quality are not produced anywhere in the country. It is pointed out that approximately 10 per cent of infant mortality in India is caused by congenital heart diseases.

As a critical treatment, surgical correction of these disease conditions, such as Tetralogy of Fallot, Pulmonary Artesia, Transposition of Great Arteries with VSD and Pulmonary Stenosis, require patches or valved conduits.

Material crunch

However, good and satisfactory substitute materials that meet the requirements for application in these critical surgical procedures are not available anywhere in the country now.

For the development of the medical devices, quality animal tissues are to be sourced from ‘low risk herd’ and KLDB is maintaining modern dairy farms complying with the quality system requirements of ISO 9001. The board is planning to upgrade its farm at Kulathupuzha to produce animal tissues of biomedical quality.

The team at SCTIMST here will de-cellularise the animal tissues received from KLDB using the process developed indigenously. These processed tissues will be evaluated through a battery of tests to ensure their safety and efficacy.

The project aims at developing ‘patch material’ from bovine pericardium and ‘valved conduit’ from bovine jugular vein that meet the international safety requirements needed for such applications.

More Stories on : Animals & Livestock | Kerala

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