Asian shares flatlined on Wednesday as worries about global recession and endless trade wars vied with hopes for a lot more monetary and fiscal stimulus to keep growth going.

Much depends on what the Federal Reserve does with US interest rates, making markets hyper-sensitive to the minutes - due later on Wednesday - of its last meeting.

Traders are also awaiting the central bank's annual Jackson Hole seminar later this week and a Group of Seven summit this weekend for clues on what additional steps policymakers will take to boost economic growth.

Morgan Stanley economist Ellen Zentner advised clients to watch for the use of the word “somewhat” when Fed Chair Powell describes further policy adjustments.

“Acknowledgment that downside risks have increased with no characterisation of 'somewhat' could be taken as confirmation that it is likely the Fed makes a larger cut in September,” Zentner wrote in a note.

Futures are fully priced for a quarter-point cut in rates next month, and over 100 basis points of easing by the end of next year.

With so much riding on the Fed, investors were understandably cautious. MSCI's broadest index of Asia-Pacific shares outside Japan dithered either side of flat after three straight days of gains.

Japan's Nikkei slipped 0.4 per cent, while Shanghai blue chips lost -0.1 per cent. Faring a bit better were E-Mini futures for the S&P 500, which added 0.25 per cent, while EUROSTOXX 50 futures edged up 0.1 per cent.

US President Donald Trump showed no signs of backing down in his tussle with China, declaring on Tuesday a confrontation was necessary even if it caused short-term harm to the US economy.

His strongly-worded remarks came hours before his government announced approval of an $8-billion sale of Lockheed Martin F-16 fighter jets to Taiwan, a move sure to draw Beijing's ire and further dim prospects for a quick trade deal.

Political turmoil in Hong Kong, Britain and Italy has also heightened uncertainties for investors. The prospect of new elections in Italy after the resignation of Prime Minister Giuseppe Conte added to jitters, sending Italian sovereign bond yields sliding.

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Alarm bells started ringing last week when yields on US 10-year notes fell below two-year yields for the first time since 2007, an inversion that has presaged previous recessions and is widely watched by markets.

That was enough to prompt Trump and his advisers to examine ways to provide a fiscal boost to the US economy, should it be deemed necessary.

In addition, the central banks of the euro zone, Australia and China are all expected to open the monetary spigot further this year, while Germany is considering fiscal stimulus.

Those prospects have driven yields lower. Benchmark US 10-year Treasury yields stood at 1.57 per cent on Wednesday from a high of 1.625 per cent on Monday.

Currency markets have been mostly subdued ahead of the Jackson Hole meeting and Fed minutes. The dollar was a shade firmer on the yen at 106.48 after losing 0.4 per cent on Tuesday, while sterling was last trading at $1.2170.

The euro trod water near Tuesday's high of $1.1101. The dollar index was on the defensive at 98.178 as it drifted away from a three-week top touched on Monday.

In commodities markets, US crude firmed 17 cents to $56.26 per barrel, while Brent added 23 cents to $60.26. Spot gold was a shade weaker at $1,503.88 an ounce.

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