Wall Street ended lower on Monday as a bounce in Apple failed to offset concerns that the US Federal Reserve could raise interest rates sooner than later.
The timing of future Fed rate hikes in the face of a sluggish economy is a major focus among stock investors who have benefited from historically low borrowing costs since the 2008 financial crisis.
The Dow Jones industrial average and the Nasdaq Composite traded higher for much of the session but they made a pronounced dip in the final few minutes.
San Francisco Fed President John Williams and his St. Louis counterpart, James Bullard, both struck hawkish tones in separate appearances on Monday.
Last week, investors were surprised at central bank minutes that opened the door to a rate hike as soon as June. Investors will listen for fresh clues to the Fed's intentions when Chair Janet Yellen speaks on Friday.
“The market needs to be coddled and gently eased into a slightly higher interest-rate environment, and that appears to be what the Fed is doing,” said Tim Ghriskey, chief investment officer of Solaris Group in Bedford Hills, New York.
“Rates need to normalise and the Fed needs to give itself room to lower again in the event of another financial crisis," Ghriskey said.
Apple rose 1.27 per cent and the Philadelphia SE Semiconductors Index added 0.66 per cent after Taiwan's Economic Daily News reported that Apple asked suppliers to build more of its next-generation iPhones than previously expected.
The Dow Jones industrial average declined 0.05 percent to end at 17,492.93 points and the S&P 500 lost 0.21 percent to 2,048.04. The Nasdaq Composite dipped 0.08 percent to 4,765.78.
Just 5.9 billion shares changed hands on US exchanges, well below the 7.2 billion daily average for the past 20 trading days, according to Thomson Reuters data.
Eight of the 10 major S&P sectors ended lower, led down by a 0.97 per cent dip in utilities.
The materials index rose 1.19 percent. It was boosted by Monsanto's 4.41-per cent jump after the US seeds company received a $62 billion takeover offer from German drugs and crop chemicals group Bayer.
The largest drag on the S&P 500 was Microsoft , down 1.17 per cent.
Saturday was the one-year anniversary of the S&P 500's last record high close and the index is now down some 4 percent from that peak.
Tightening borrowing costs would help choke inflation but also hamper economic expansion and reduce liquidity in stock markets, which could impede stock gains.
The S&P 500 is trading at about 16.4 times expected earnings, down from about 17 at the start of May, according to Thomson Reuters Datastream.
Tribune Publishing fell 15.04 percent after it rejected Gannett's latest takeover offer. Gannett was down 2.36 per cent.
Advancing issues outnumbered decliners on the NYSE by 1,521 to 1,479. On the Nasdaq, 1,489 issues rose and 1,329 fell.
The S&P 500 index showed six new 52-week highs and no new lows, while the Nasdaq recorded 46 new highs and 27 new lows.