Japan's Nikkei share average dropped on Friday, dragged down by caution towards the US jobs report due later in the day and as the yen erased earlier losses and firmed.
Traders said selling of equity positions intended to generate dividend payments for exchanged-traded funds also weighed on the market.
The Nikkei fell 1.1 per cent to 15,106.98. The index lost 3.7 per cent for the week, during which concerns about Brexit resurfaced and hurt global equities.
Gaming group Nintendo Co outperformed on Friday, rising 8.9 per cent on expectations that its recently-launched Pokemon GO mobile game would attract significant demand in the rapidly growing mobile gaming segment.
The broader Topix dropped 1.3 per cent to 1,209.88 and the JPX-Nikkei Index 400 lost 1.4 per cent to 10,893.60.