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Covid inoculation: DCGI nod for CMC plan to study mixing of Covishield and Covaxin

Our Bureau New Delhi | Updated on August 11, 2021

CMC proposal was earlier approved by independent panel affiliated to drugs regulator

The Drugs Controller General of India (DCGI) is learnt to have approved a proposal from the Christian Medical College (CMC), Vellore, to carry out trials on mixed use of Covid-19 vaccines — Covishield and Covaxin — in people.

This is significant because studies elsewhere have shown that when people are given doses of AstraZeneca and Pfizer-BioNTech vaccine as first and second doses, the inoculation was found to be more effective, triggering better immunity to various strains.

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CMC Vellore’s proposal follows an accidental mixing of Covishield and Covaxin doses in 18 patients in Siddharth Nagar in Uttar Pradesh. This event prompted the Indian Council of Medical Research (ICMR) to look into the mishap. The apex medical research body is believed to have found that giving an adenovirus-vector vaccine (Covishield) followed by an inactivated whole virus vaccine was not only safe but more immunogenic.

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The CMC proposal was earlier approved by the independent expert committee affiliated to the drugs regulator.

Published on August 11, 2021

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