The rupee on Tuesday showed signs of fatigue after a two-day upmove and ended three paise lower at 64.40 against the US currency in a quiet session ahead of key macro data amid sustained capital outflows. Participants preferred to stay on the sidelines awaiting further cues ahead of retail inflation and industrial production data. The key macroeconomic data was released after market hours. Further, currency traders and speculators also remained cautious ahead of the two-day US Fed policy meeting that will end on Wednesday. The Federal Reserve is widely expected to hike key interest rates for the third time this year.

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