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Takeda-led Covid-19 plasma treatment enters clinical trial with first patient

Reuters | | Updated on: Oct 09, 2020
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The phase 3 trial by the CoVIg Plasma Alliance will enrol 500 adult patients from US, Mexico and 16 other countries

Japan’s Takeda Pharmaceutical Co said on Friday an alliance of drugmakers it spearheads has enrolled its first patient in a global clinical trial of a blood plasma treatment for Covid-19 after months of regulatory delays.

The phase 3 trial by the group, known as the CoVIg Plasma Alliance, aims to enrol 500 adult patients from the United States, Mexico and 16 other countries, according to a statement.

Patients will be treated with Gilead Science Inc’s Remdesivir alongside the plasma treatment, which will be provided by CSL Behring, Takeda and two other companies.

“We are hopeful that data from the clinical trial will be available before the end of the year,” Bill Mezzanotte, chief medical officer of CSL Behring, said in the release.

Also read: SARS-CoV-2 adopts 10 structural states to target ACE2 receptors in humans: Study

The group had aimed to begin the clinical trial in July, but it was delayed pending regulatory approval. The National Institutes of Health in the US is the trial’s sponsor.

The alliance, which also includes Germany’s Biotest AG and Octapharma Plasma, is working on a hyperimmune globulin therapy derived from the blood plasma of people who have recovered from Covid-19.

It offers a standardised dose of antibodies and doesn’t need to be limited to patients with matching blood types.

Published on October 09, 2020

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